Status:
UNKNOWN
Gene-expression Profiles in CNS-metastatic Non-small Cell Lung Cancer
Lead Sponsor:
National Institute of Cancerología
Conditions:
Brain Disease
Metastasis
Eligibility:
All Genders
18+ years
Brief Summary
Non small-cell lung cancer (NSCLC) accounts 85% of all lung cancer.The development of brain metastasis diminished life expectancy to less than one year with a median survival of less than three months...
Detailed Description
Brain metastases occur in 30-50% of lung adenocarcinoma (LAC) patients and confer a worse prognosis and quality of life. A better selection of in-risk patients through a more accurate biomarker could ...
Eligibility Criteria
Inclusion
- Age \> 18 years
- With auto-sufficiency
- Biopsy procedure approved
- Any TNM status
- Consulting at the National Institutes of Cancerology or Respiratory Diseases
- Informed consent signed
Exclusion
- Comorbidity with other cancer type, hereditary or autoimmune diseases and treatment with immunosuppressor drugs
- Previous treatment with adjuvant or neoadjuvant chemo- or radiotherapy
- No specimen availability
- No diagnosis of non-small-cell lung cancer at histopathology sample
Key Trial Info
Start Date :
March 1 2008
Trial Type :
OBSERVATIONAL
Allocation :
ESTIMATED
End Date :
December 1 2012
Estimated Enrollment :
120 Patients enrolled
Trial Details
Trial ID
NCT00862173
Start Date
March 1 2008
End Date
December 1 2012
Last Update
June 12 2012
Active Locations (2)
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1
Instituto Nacional de Cancerología
Mexico City, Mexico, 14080
2
Instituto Nacional de Enfermedades Respiratorias
Mexico City, Mexico, 14080