Status:

COMPLETED

Oral Acetazolamide, Brimonidine Tartarate, and Anterior Chamber Paracentesis for Ocular Hypertension Control After Intravitreal Bevacizumab

Lead Sponsor:

University of Sao Paulo

Collaborating Sponsors:

Fundação de Apoio ao Ensino Pesquisa e Assitência do HCFMRPUSP

Conditions:

Age Related Macular Degeneration

Diabetic Retinopathy

Eligibility:

All Genders

18+ years

Phase:

PHASE2

Brief Summary

The purpose of this study is to evaluate the effects of anterior chamber paracentesis, brimonidine and oral acetazolamide to reduce intra-ocular pressure variations after intravitreal bevacizumab inje...

Eligibility Criteria

Inclusion

  • Diagnosis of age related macular disease or diabetic retinopathy
  • Able and willing to provide informed consent

Exclusion

  • History of ocular hypertension or glaucoma
  • High Myopes (\> 6 spherical diopters)
  • High Hyperopes (\> 4 spherical diopters)
  • Pulmonary disease
  • Renal disease
  • Known allergy to any component of the study drug
  • Myocardial infarction, transient ischemic attack within 4 months prior to randomization or any contraindication for bevacizumab use

Key Trial Info

Start Date :

June 1 2008

Trial Type :

INTERVENTIONAL

Allocation :

ACTUAL

End Date :

March 1 2009

Estimated Enrollment :

56 Patients enrolled

Trial Details

Trial ID

NCT00864838

Start Date

June 1 2008

End Date

March 1 2009

Last Update

March 19 2009

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