Status:
COMPLETED
The Neuroprotective Effects of RPC on the Neurosurgery
Lead Sponsor:
Xijing Hospital
Conditions:
s100b
Eligibility:
All Genders
20-70 years
Phase:
PHASE1
Brief Summary
The current study is designed to clarify the neuroprotective effect of remote ischemic precondtioning on the patients underwent neurosurgery.
Detailed Description
BACKGROUND: Brain ischemia and injury are commonly contributed to perioperative morbidity and mortality after neurosurgery. Remote ischemic preconditioning (RIPC) is a phenomenon whereby brief periods...
Eligibility Criteria
Inclusion
- Patients referred for primary elective neurosurgery were invited to participate in the study at the time of scheduling for operation
Exclusion
- Potential participants were excluded if they were \>70 years of age
- Required concomitant procedures other than neurosurgery
- Had experienced an acute coronary syndrome or myocardial infraction within 3 months
- Were unable to give informed consent
- Were taking sulfonylurea oral hypoglycemic agents or nicorandil drug therapy because these agents have been shown to effect preconditioning.
Key Trial Info
Start Date :
September 1 2008
Trial Type :
INTERVENTIONAL
Allocation :
ACTUAL
End Date :
September 1 2009
Estimated Enrollment :
70 Patients enrolled
Trial Details
Trial ID
NCT00866489
Start Date
September 1 2008
End Date
September 1 2009
Last Update
December 28 2010
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