Status:

COMPLETED

Human Liver Explants for HIF-1 Alpha Analysis/Comparison (HIF HCC)

Lead Sponsor:

Northwestern University

Collaborating Sponsors:

Northwestern University Feinberg School of Medicine

Conditions:

Liver Cancer

Eligibility:

All Genders

18+ years

Brief Summary

The purpose of the study is to compare levels of HIF-1 α (Hypoxia Inducing Factor 1-alpha) in patients who have been treated with various types of liver cancer treatments.

Detailed Description

In the currently ongoing retrospective aspect of the study, we will obtain pathologic tumor explant specimens from the tumor explant population from 8/1/1994 to 12/31/2005. We will prepare 5-10 slides...

Eligibility Criteria

Inclusion

  • Adults, any gender ≥ to 18 years of age
  • Previous, or current diagnosis of hepatocellular carcinoma (clinical or biopsy proven)
  • Resection for hepatoma and/or transplant
  • Patients with diagnosis of hepatocellular carcinoma from 8/1/94 thru 12/31/05 (retrospective) with biopsy, explant and/or liver transplantation here at Northwestern Memorial Hospital (NMH).
  • Patients previously diagnosed or, recently diagnosed with liver cancer that were treated, currently are being treated our will potentially undergo treatment for the disease.

Exclusion

  • Any subject outside of the above inclusion criteria

Key Trial Info

Start Date :

February 1 2006

Trial Type :

OBSERVATIONAL

Allocation :

ACTUAL

End Date :

July 1 2019

Estimated Enrollment :

180 Patients enrolled

Trial Details

Trial ID

NCT00866957

Start Date

February 1 2006

End Date

July 1 2019

Last Update

November 18 2023

Active Locations (1)

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1

Northwestern Memorial Hospital

Chicago, Illinois, United States, 60611