Status:
TERMINATED
Heading Off Peripheral Neuropathy With Exercise
Lead Sponsor:
University of Nebraska
Conditions:
Peripheral Nervous System Disorders
Breast Neoplasms
Eligibility:
All Genders
19+ years
Phase:
NA
Brief Summary
Chemotherapy for the treatment of breast cancer can affect nerves and muscles leading to loss of sensation in the hands and feet for feeling hot and cold, difficulty walking, and muscle weakness. This...
Detailed Description
This pilot study will test the effects of a tailored home-based walking (aerobic) and strength training (resistance) exercise program for individuals receiving taxane-based chemotherapy for breast can...
Eligibility Criteria
Inclusion
- age 19 or older with newly diagnosed Stage I-IIIa invasive breast cancer who are to be treated with a taxane-based chemotherapy regimen (with paclitaxel or docetaxel) and thus are at risk for the development of CIPN.
Exclusion
- any disease (e.g. diabetes, HIV) that results in peripheral neuropathy;
- any disease or disorder that results in muscle weakness (such as chronic fatigue syndrome, multiple sclerosis, spinal cord tumors or injuries, stroke, preexisting cardiopulmonary disease);
- any disease or disorder that would preclude strength training exercises (such as bone metastasis, osteoporosis);
- individuals with diagnosed lymphedema or advanced disease (\> Stage IIIa, or metastatic disease) at high risk for bone metastases and pathologic fracture will be excluded.
Key Trial Info
Start Date :
March 25 2009
Trial Type :
INTERVENTIONAL
Allocation :
ACTUAL
End Date :
December 13 2011
Estimated Enrollment :
19 Patients enrolled
Trial Details
Trial ID
NCT00869804
Start Date
March 25 2009
End Date
December 13 2011
Last Update
December 5 2023
Active Locations (1)
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1
University of Nebraska Medical Center
Omaha, Nebraska, United States, 68198