Status:

COMPLETED

Study of 400mcg Sublingual Versus 400mcg Buccal Misoprostol Following 200mg Mifepristone for Medical Abortion up to 63 Days Last Menstrual Period (LMP)

Lead Sponsor:

Gynuity Health Projects

Conditions:

Abortion, Induced

Eligibility:

FEMALE

18+ years

Phase:

NA

Brief Summary

This open-label, randomized study is being conducted to determine whether a dose of 400 mcg of buccal misoprostol (i.e., in the cheek) taken 24 hours following administration of mifepristone 200 mg is...

Eligibility Criteria

Inclusion

  • Gestational age less than or equal to 63 days
  • General good health including absence of conditions which contraindicate the use of mifepristone and misoprostol for pregnancy termination; and
  • Willing to provide an address and/or telephone number for purposes of follow-up.

Exclusion

  • Confirmed or suspected ectopic pregnancy or undiagnosed adnexal mass
  • IUD in place
  • Chronic renal failure
  • Concurrent long-term corticosteroid therapy
  • History of allergy to mifepristone, misoprostol or other prostaglandin
  • Hemorrhagic disorders or concurrent anticoagulant

Key Trial Info

Start Date :

July 1 2007

Trial Type :

INTERVENTIONAL

Allocation :

ACTUAL

End Date :

March 1 2009

Estimated Enrollment :

550 Patients enrolled

Trial Details

Trial ID

NCT00870272

Start Date

July 1 2007

End Date

March 1 2009

Last Update

March 27 2009

Active Locations (1)

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1

State University of Medicine and Pharmacy

Chisinau, Moldova