Status:
WITHDRAWN
Pilot Study Evaluating Stress Response and Immune Function in Mechanically Ventilated Patients With Alcohol Use Disorders Treated With Propofol or Midazolam
Lead Sponsor:
Virginia Commonwealth University
Conditions:
Alcoholism
Respiration, Artificial
Eligibility:
All Genders
18+ years
Phase:
PHASE4
Brief Summary
The aim of this study is to evaluate the effects of the sedatives propofol and midazolam on stress response and immune function in critically ill patients with alcohol use disorders who are undergoing...
Detailed Description
No detailed description
Eligibility Criteria
Inclusion
- Diagnosis of alcohol use disorders
- Need for invasive mechanical ventilation
- Need for continuous intravenous infusion of sedative(s)
Exclusion
- Age \< 18 years
- Pregnant women
- Prisoners
- Receiving propofol prior to randomization
- Patient experiencing active alcohol withdrawal
- Immunosuppression
- Shock
- Attending physician does not feel patient is candidate to receive either propofol or midazolam
- Patient has contraindication(s) to receiving either propofol or midazolam
- Inability to enroll patient within 96 hours after initiation of mechanical ventilation
- Transfer from another intensive care unit
Key Trial Info
Start Date :
March 1 2009
Trial Type :
INTERVENTIONAL
Allocation :
ACTUAL
End Date :
March 1 2009
Estimated Enrollment :
Patients enrolled
Trial Details
Trial ID
NCT00871039
Start Date
March 1 2009
End Date
March 1 2009
Last Update
March 1 2016
Active Locations (2)
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1
Virginia Commonwealth University Medical Center (formerly known as Medical College of Virginia)
Richmond, Virginia, United States, 23298
2
Virginia Commonwealth University Medical Center
Richmond, Virginia, United States, 23298