Status:

COMPLETED

Confocal Probe-based Endoscopic Imaging, Colorectal Cancer, Gastrointestinal (GI) Pathologies

Lead Sponsor:

Mayo Clinic

Collaborating Sponsors:

American Society for Gastrointestinal Endoscopy

Conditions:

Colonic Polyps

Esophageal Diseases

Eligibility:

All Genders

18+ years

Brief Summary

The recently developed endoscopic Confocal probe microscopy system allows imaging of surface epithelium during ongoing endoscopy (upper and lower) with the potential of immediate diagnosis of various ...

Detailed Description

Colorectal cancer is the second most common cause of cancer-related death in the U.S. Although removal of pre-malignant polyps has been shown to reduce the risk of colorectal cancer, up to 50% of remo...

Eligibility Criteria

Inclusion

  • Ages 18 to 100
  • Any patient undergoing screening and/or surveillance colonoscopy and/or upper endoscopy with possible biopsy or removal of tissue by polypectomy

Exclusion

  • Unwilling to consent
  • Allergy to fluorescein
  • Lack of any pathological state that would require biopsy at the time of endoscopy (will be considered "screen failure" since this will not be known until after consent is obtained and sedated endoscopy performed)
  • Women of child-bearing age who are sexually active and not practicing an acceptable form of contraception

Key Trial Info

Start Date :

March 1 2008

Trial Type :

OBSERVATIONAL

Allocation :

ACTUAL

End Date :

June 1 2012

Estimated Enrollment :

225 Patients enrolled

Trial Details

Trial ID

NCT00874263

Start Date

March 1 2008

End Date

June 1 2012

Last Update

June 22 2012

Active Locations (1)

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Mayo Clinic

Jacksonville, Florida, United States, 32224