Status:
UNKNOWN
Allicin Bioavailability From Garlic Supplements and Garlic Foods
Lead Sponsor:
Silliker, Inc.
Collaborating Sponsors:
National Center for Complementary and Integrative Health (NCCIH)
Conditions:
Healthy
Eligibility:
All Genders
18-72 years
Phase:
EARLY_PHASE1
Brief Summary
This study will measure the bioavailability of allicin, the main active compound of garlic, from garlic supplements and garlic foods (raw, cooked, processed) so that * supplement manufacturers and cl...
Detailed Description
The bioavailability of allicin, the main active compound of garlic, from garlic supplements and garlic foods is highly questionable and unpredictable from in vitro tests, due to dependence upon alliin...
Eligibility Criteria
Inclusion
- in good health (self-judged)
- BMI (body mass index): 19-32 kg/m2
- not planning to move out of the area in the next year
- willing to abstain from consuming garlic and onion and foods that contain them for two days prior to and during each test (diet restrictions)
- able to deliver bags of breath to the research facility five times in two days
- willing to eat whole wheat tuna sandwiches
Exclusion
- known serious health problems: diabetes, heart disease, active neoplasms, renal or liver disease, hyper- or hypothyroidism, breathing disorders, gastroesophageal reflux disease (GERD), gastrointestinal disease (absorption interference)
- known allergy to garlic or wheat
- tobacco user
- excessive alcohol intake (³2 drinks/day, self-reported)
- unable to speak English well
Key Trial Info
Start Date :
April 1 2009
Trial Type :
INTERVENTIONAL
Allocation :
ESTIMATED
End Date :
April 1 2011
Estimated Enrollment :
12 Patients enrolled
Trial Details
Trial ID
NCT00874666
Start Date
April 1 2009
End Date
April 1 2011
Last Update
November 20 2009
Active Locations (1)
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1
Silliker, Inc.
Orem, Utah, United States, 84058