Status:
RECRUITING
Development of IPS from Donated Somatic Cells of Patients with Neurological Diseases
Lead Sponsor:
Hadassah Medical Organization
Conditions:
Neurodegenerative Disorders
Eligibility:
All Genders
18+ years
Brief Summary
Human fibroblasts and possibly other human somatic cells may be reprogrammed into induced pluripotent stem (iPS) cells by the forced expression of transcription factors (1-5). The iPS cells seem to sh...
Detailed Description
The derivation of human iPS cells (1-5) open new avenues to model human diseases since it may now be possible to develop iPS cells from the fibroblasts or other somatic cells of patients with various ...
Eligibility Criteria
Inclusion
- Donors suffering from different (specified) neurodegenerative disorders scheduled to undergo surgery for medical reasons or will donate a single or a few hairs--to be removed intact from the scull or other areas in the body.
- Healthy donors scheduled to undergo surgery for medical reasons or will donate a single or a few hairs--to be removed intact from the scull or other areas in the body.
Exclusion
- None
Key Trial Info
Start Date :
April 1 2009
Trial Type :
OBSERVATIONAL
Allocation :
ESTIMATED
End Date :
December 1 2030
Estimated Enrollment :
120 Patients enrolled
Trial Details
Trial ID
NCT00874783
Start Date
April 1 2009
End Date
December 1 2030
Last Update
March 4 2025
Active Locations (1)
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1
Hadassah Ein Kerem
Jerusalem, Israel, Israel, 9112100