Status:

COMPLETED

Diabetes Mellitus Type 2 Basal Insulin Dosing Requirements Study

Lead Sponsor:

Diabetes Care Center

Collaborating Sponsors:

Animas Corporation

Conditions:

Type 2 Diabetes Mellitus

Eligibility:

All Genders

18+ years

Phase:

NA

Brief Summary

The main purpose of this study is to determine the number of daily basal insulin rate changes that are needed to achieve short-term near normal glucose control in insulin pump patients with type 2 dia...

Detailed Description

Subjects will be taught CHO counting after which they will be introduced to an insulin pump. They will wear the insulin pump for three weeks to adjust to the pump and its functions. Then the subject w...

Eligibility Criteria

Inclusion

  • Inclusion Criteria:
  • Type 2 diabetes \> 3month duration
  • Age 18
  • Hb A1C \<12%
  • On any hypoglycemic therapy including insulin for 5 patients and 5 patients naive to insulin and failing oral treatment
  • Normal creatine
  • Negative for GAD antibodies
  • SMBG \>4/d and willing/able to comply with study requirements
  • Demonstrated adherence to visits and instructions.
  • Exclusion Criteria
  • Severe hypoglycemic during the last month
  • Severe cardiac, pulmonary or cerebral disease
  • Demonstrated non compliance with clinical recommendations
  • Pregnancy, nursing or women who could potentially become pregnant
  • Presence of physical, psychological or cognitive impairments that would interfere with adherence to an intensive insulin therapy program or compliance with dietary, diary keeping or maintenance of CGM sensor or pump

Exclusion

    Key Trial Info

    Start Date :

    March 1 2009

    Trial Type :

    INTERVENTIONAL

    Allocation :

    ACTUAL

    End Date :

    December 1 2011

    Estimated Enrollment :

    30 Patients enrolled

    Trial Details

    Trial ID

    NCT00874809

    Start Date

    March 1 2009

    End Date

    December 1 2011

    Last Update

    August 27 2013

    Active Locations (1)

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    Diabetes Care Center

    Salinas, California, United States, 93901