Status:
UNKNOWN
Study of Ocular Blood Flow in Patients With Glaucoma and/or Obstructive Sleep Apnea Syndrome (OSAS)
Lead Sponsor:
University Hospital, Grenoble
Conditions:
Obstructive Sleep Apnea Syndrome
Eligibility:
All Genders
18-80 years
Phase:
NA
Brief Summary
Obstructive sleep apnea syndrome (OSAS) is a common disease, with a prevalence evaluated between 5 - 7% in the general population. OSAS is characterized by recurrent episodes of partial or complete up...
Detailed Description
JUSTIFICATION OF THE PROJECT Obstructive sleep apnea syndrome (OSA) is an under diagnosed disease affecting 5% of the general population. This disease is associated with an increase in the risk for ca...
Eligibility Criteria
Inclusion
- the age is between 18 years \& 80 years
- nobody affiliated with social security
- including informed \& signed consent
Exclusion
- congenital malformation leading to an excavation of the optic nerve or a deficit of the visual field
- any eye disease associated, including refraction disorder ( \> 4 diopters) , retinal disease, cataract, corneal opacity)
- taking medication which can have an action on blood pressure or regulation ( vasoconstrictors, vasodilators, beta-agonists and antagonists, nitrates, theophylline, dipyridamole, sildenafil, immunosuppressive, corticosteroid or Non-steroidal anti-inflammatory drugs (\> 10 days), hormonal therapy), sedative drug (antidepressive, anxiolytics, hypnotics) drops with activity on regulation of ocular pressure ( beta-blockers)
- all ophthalmic drops
- pregnancy
- current infection ( acute hepatitis B, hepatitis C active, HIV infection)
- known hypertension or suspected
- Electrolyte disturbance
- Pathology that can affect the regulation of blood pressure : parkinson' disease, patients transplanted kidney or cardiac arrhythmias, severe heart failure atrial fibrillation or frequent extrasystole (\> 10 / minute)
- nocturnal Professional activity
- History of surgery or carotid stenting
- Previous treatment of Obstructive Sleep Apnea Syndrome by continuous positive pressure, propulsion prosthesis mandibular or maxillofacial surgery
- No predictable compliance with the protocol
- Patients participating in another biomedical research
- Patients with no affiliation to social security
- narrow irido corneal angle
Key Trial Info
Start Date :
September 1 2006
Trial Type :
INTERVENTIONAL
Allocation :
ESTIMATED
End Date :
January 1 2014
Estimated Enrollment :
90 Patients enrolled
Trial Details
Trial ID
NCT00874913
Start Date
September 1 2006
End Date
January 1 2014
Last Update
October 10 2012
Active Locations (1)
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1
Chu de Grenoble
Grenoble, France, 38043