Status:
COMPLETED
Neurogenic Mechanisms in Burning Mouth Syndrome
Lead Sponsor:
University of Copenhagen
Conditions:
Burning Mouth Syndrome
Eligibility:
FEMALE
18-70 years
Phase:
NA
Brief Summary
Burning mouth syndrome (BMS) is characterized by a bilateral burning sensation in the anterior tongue, hard palate and lips in the absence of any clinical or laboratory findings. The term syndrome imp...
Detailed Description
Data which support the hypothesis that BMS is a neuropathic pain condition include amongst others a recent clinically controlled study that has shown up-regulation of TRPV1-positive nerve fibres in to...
Eligibility Criteria
Inclusion
- non-smoking female patients with burning mouth syndrome (n=26)
- healthy aged-matched control group (n=10)
Exclusion
- pregnancy and lactation (inclusion requires negative pregnancy test)
- women who do not use safe anticonception
- patients with know allergy/hypersensitivity to capsicum and other capsaicinoid-containing products
- Active infection which requires antibiotic treatment
- use of mouthrinse. The use of these is stopped 14 days before inclusion
- patients who are able to give informed consent due to physical or mental disabilities
Key Trial Info
Start Date :
January 1 2009
Trial Type :
INTERVENTIONAL
Allocation :
ACTUAL
End Date :
June 1 2010
Estimated Enrollment :
22 Patients enrolled
Trial Details
Trial ID
NCT00875537
Start Date
January 1 2009
End Date
June 1 2010
Last Update
March 14 2017
Active Locations (1)
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1
Department of Odontology, Section of Oral Medicine, Clinical Oral Physiology, Oral Pathology & Anatomy
Copenhagen, Denmark, 2200