Status:

COMPLETED

Randomized, Controlled Study Evaluating CERE-110 in Subjects With Mild to Moderate Alzheimer's Disease

Lead Sponsor:

Sangamo Therapeutics

Collaborating Sponsors:

Alzheimer's Disease Cooperative Study (ADCS)

Conditions:

Alzheimer's Disease

Eligibility:

All Genders

55-80 years

Phase:

PHASE2

Brief Summary

The purpose of this study is to evaluate the potential benefits of CERE-110 in the treatment of Alzheimer's disease. CERE-110 is an experimental drug that is designed to help nerve cells in the brain ...

Eligibility Criteria

Inclusion

  • Diagnosis of mild to moderate Alzheimer's disease
  • Approved medications for Alzheimer's disease may be taken if the dose has been stable for 3 months
  • A study partner who can attend all study visits
  • Good general health
  • Medically able to undergo neurosurgery

Exclusion

  • Significant neurological disease other than Alzheimer's disease
  • Significant depression or other psychiatric disorder
  • Unstable medical conditions

Key Trial Info

Start Date :

November 1 2008

Trial Type :

INTERVENTIONAL

Allocation :

ACTUAL

End Date :

August 13 2015

Estimated Enrollment :

49 Patients enrolled

Trial Details

Trial ID

NCT00876863

Start Date

November 1 2008

End Date

August 13 2015

Last Update

December 21 2020

Active Locations (10)

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Page 1 of 3 (10 locations)

1

University of Alabama

Birmingham, Alabama, United States, 35294

2

University of California, Los Angeles

Los Angeles, California, United States, 90095

3

University of California, San Diego

San Diego, California, United States, 92037

4

Georgetown University

Washington D.C., District of Columbia, United States, 20007