Status:

COMPLETED

Effect of Vitamin D Supplementation on Fasting Glucose and Interleukin-10 (IL-10) in Arab Women With Impaired Fasting Glucose

Lead Sponsor:

Clalit Health Services

Collaborating Sponsors:

Rambam Health Care Campus

Conditions:

Obesity

Eligibility:

FEMALE

40-65 years

Phase:

PHASE4

Brief Summary

Obesity, and its metabolic consequences - impaired fasting glucose (IFG) and diabetes, is highly prevalent among Arab women in Israel and the Middle East. Since life style modification is difficult to...

Detailed Description

Eligible women will be invited by their primary care physician to participate in the study. After signing an informed consent women will be randomized to receive oral vitamin D 100,000 IU or similar p...

Eligibility Criteria

Inclusion

  • Arab women, age 40-65
  • No significant handicap or disabilities in ADL
  • BMI \> 25 kg/m2
  • IFG of 100-125 mg/dl

Exclusion

  • Diabetes Mellitus
  • Other medical conditions that may have an effect on IFG (cancer, chronic renal failure, inflammatory diseases etc)
  • History of vascular disease
  • Regular use of medications that may affect IFG (steroids, HRT, diuretics etc)
  • Hypercalcemia (albumin corrected Ca \>10.3 mg/dl)
  • Inability to sign an informed consent due to mental or psychiatric ailment

Key Trial Info

Start Date :

June 1 2009

Trial Type :

INTERVENTIONAL

Allocation :

ACTUAL

End Date :

October 1 2009

Estimated Enrollment :

74 Patients enrolled

Trial Details

Trial ID

NCT00877123

Start Date

June 1 2009

End Date

October 1 2009

Last Update

November 10 2011

Active Locations (1)

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Clalit Health Services, Haifa and Western Galilee District

Haifa, Israel