Status:
COMPLETED
Examining Physiology and Brain Function in People With the Fragile X Premutation
Lead Sponsor:
University of California, Davis
Collaborating Sponsors:
National Institute of Mental Health (NIMH)
Conditions:
Fragile X Premutation
Eligibility:
MALE
18-45 years
Brief Summary
This study will examine whether individuals with the fragile X genetic premutation are likely to have emotional, social, and memory deficits and how the brain may be involved in these deficits.
Detailed Description
FMR1 is a gene associated with fragile X syndrome-the most common cause of mental retardation-and with social, emotional, and cognitive deficits. The chance of developing these deficits depends on the...
Eligibility Criteria
Inclusion
- Possesses FMR1 premutation or is part of the general population control group
- Normal or corrected vision
- Speaks English
Exclusion
- Presence of contraindication for brain MRI, such as having metal in the body
- Presence of a major medical condition, such as kidney, heart, or liver disease
- Presence of a neurological disorder
- Current alcohol or drug abuse or dependence
- History of head trauma
- History of brain infection
- Medication affecting cerebral blood flow
Key Trial Info
Start Date :
June 1 2007
Trial Type :
OBSERVATIONAL
Allocation :
ACTUAL
End Date :
February 1 2013
Estimated Enrollment :
110 Patients enrolled
Trial Details
Trial ID
NCT00879502
Start Date
June 1 2007
End Date
February 1 2013
Last Update
May 30 2017
Active Locations (1)
Enter a location and click search to find clinical trials sorted by distance.
1
M.I.N.D. Institute, U.C. Davis
Sacramento, California, United States, 95817