Status:
COMPLETED
Strength Training in Walking Tolerance in Intermittent Claudication Patients
Lead Sponsor:
University of Sao Paulo
Collaborating Sponsors:
Fundação de Amparo à Pesquisa do Estado de São Paulo
Conditions:
Peripheral Arterial Disease
Hypertension
Eligibility:
All Genders
50-85 years
Phase:
PHASE3
Brief Summary
Background: Muscle atrophy and reduced leg strength are related to exercise intolerance in patients with intermittent claudication (IC), suggesting that strength training (ST) could improve exercise p...
Detailed Description
From July 2005 to December 2006, three hundred patients with peripheral arterial disease, who were enrolled in a tertiary center specialized in vascular disease and were able to walk for at least 2 mi...
Eligibility Criteria
Inclusion
- Fontaine stage II peripheral arterial disease(14)
- Symptoms of intermittent claudication for at least 6 months
- Ankle/brachial index (ABI) at rest ≤ 0.90 in 1 or 2 legs
- Reduction of ABI after treadmill test
- Exercise tolerance limited by intermittent claudication
Exclusion
- Presence of chronic lung disease
- Inability to obtain ABI measurement due to noncompressible vessels
- Exercise tolerance limited by factors other than claudication (e.g., dyspnea or orthopedic problems)
- Poorly controlled blood pressure
- Presence of electrocardiogram response suggestive of myocardial ischemia during the exercise test
- History of revascularization in the previous year
Key Trial Info
Start Date :
July 1 2005
Trial Type :
INTERVENTIONAL
Allocation :
ACTUAL
End Date :
December 1 2008
Estimated Enrollment :
34 Patients enrolled
Trial Details
Trial ID
NCT00879697
Start Date
July 1 2005
End Date
December 1 2008
Last Update
December 15 2016
Active Locations (1)
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1
Raphael Dias
São Paulo, São Paulo, Brazil, 05588000