Status:

COMPLETED

A Trial of CM-AT in Children With Autism

Lead Sponsor:

Curemark

Conditions:

Autism

Eligibility:

All Genders

3-8 years

Phase:

PHASE3

Brief Summary

The purpose of this study is to determine whether CM-AT is safe and effective in treating the core symptoms of autism.

Detailed Description

Autism is currently a significant cause of disability in the pediatric population. Treatment is based upon the observation that many children with autism do not digest protein. CM-AT is a proprietary ...

Eligibility Criteria

Inclusion

  • Meets the current Diagnostic and Statistical Manual for Mental Disorders (DSM-IV-TR) diagnostic criteria for autistic disorder (AD)

Exclusion

  • Patient weighing \< 11kg (24.2 lbs.)
  • Demonstrated previous allergy to porcine (pork) products
  • Previous history of severe head trauma or stroke, seizure within one year of entering study or uncontrolled systemic disease
  • Diagnosis of: HIV, cerebral palsy, endocrine disorder, pancreatic disease
  • Within 30 days of starting the study, certain supplementation, chelation or dietary restriction (a 30 day washout period would be required for inclusion)
  • Use of of any stimulant medication must be discontinued 5 days prior to entering the study.
  • Subject must have a stable dose of SSRI's for at least 30 days.

Key Trial Info

Start Date :

May 1 2009

Trial Type :

INTERVENTIONAL

Allocation :

ACTUAL

End Date :

September 1 2011

Estimated Enrollment :

182 Patients enrolled

Trial Details

Trial ID

NCT00881452

Start Date

May 1 2009

End Date

September 1 2011

Last Update

April 19 2018

Active Locations (19)

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Page 1 of 5 (19 locations)

1

Southwest Autism Research and Resource Center

Phoenix, Arizona, United States, 85006

2

University of California, Davis, M.I.N.D. Institute

Sacramento, California, United States, 95817

3

University of California, San Francisco

San Francisco, California, United States, 94143

4

Neuropsychiatric Research Center of Orange County

Santa Ana, California, United States, 92701