Status:
TERMINATED
Proton Therapy With Chemotherapy for Stage III Non-Small Cell Lung Cancer (LU02)
Lead Sponsor:
University of Florida
Conditions:
Non-Small Cell Lung Cancer
Eligibility:
All Genders
18+ years
Phase:
NA
Brief Summary
The purpose of this study is to find out what effects, good and/or bad, proton radiation at a higher tumor dose (and lower normal surrounding lung dose) combined with standard chemotherapy has on lung...
Eligibility Criteria
Inclusion
- Histologically or cytologically documented non-small cell carcinoma of the lung diagnosed within 16 weeks prior to study enrollment.
- Patient must be at least 18 years old at the time of consent.
- Stage III A or III B disease.
- Patients must be able to start study treatment within 6 weeks of study enrollment.
- Induction chemotherapy is allowed.
- Marginally resectable or unresectable at presentation.
- If the patient had exploratory thoracotomy, it must be done at least 3 weeks prior to enrollment.
Exclusion
- Evidence of distant metastasis.
- Prior thoracic radiotherapy.
- Any history of allergic reaction to taxanes.
- Prior tumor resection. Candidate for upfront curative surgery.
- Pleural effusion visible on chest x-ray or the scout view of the CT chest.
- Unintentional weight loss within the month prior to diagnosis ≥ 10%.
- Previous or concomitant malignancy other than early stage tumor treated more than 3 years ago for cure.
- The presence of PET positive contralateral hilar disease.
Key Trial Info
Start Date :
June 1 2009
Trial Type :
INTERVENTIONAL
Allocation :
ACTUAL
End Date :
October 1 2014
Estimated Enrollment :
15 Patients enrolled
Trial Details
Trial ID
NCT00881712
Start Date
June 1 2009
End Date
October 1 2014
Last Update
September 11 2017
Active Locations (1)
Enter a location and click search to find clinical trials sorted by distance.
1
University of Florida Proton Therapy Institute
Jacksonville, Florida, United States, 32206