Status:
COMPLETED
A Pilot Study to Evaluate the Glucagon-Like Peptide 1 Response to the Challenge of Mixed Meals in Chinese Subjects
Lead Sponsor:
Taipei Veterans General Hospital, Taiwan
Conditions:
Healthy
Eligibility:
All Genders
20-65 years
Brief Summary
The purpose of the study is to standardize a meal test to facilitate future studies of the postprandial glucagons-like peptide 1 (GLP-1) response in Chinese subjects. Eighteen healthy Chinese subjects...
Detailed Description
Glucagon-like peptide 1 (GLP-1) is a 30-amino acid peptide produced in the intestinal epithelial endocrine L-cells. It stimulates insulin and suppresses glucagons secretion, inhibits gastric emptying,...
Eligibility Criteria
Inclusion
- Men or women aged 20 \~ 65 years old.
- Willing to participate by signing an informed consent.
- Willing to undergo two standardized mixed meal test at two separate visits
Exclusion
- Patients of known history of type 2 diabetes.
- History of major renal, liver, heart, blood and neurological disease.
- History of alcoholism or drug abuse.
- Women who are pregnant.
- Current or concomitant illness that would interfere with the subject's ability to perform the study or that would confound the study results, judged by the investigation physicians.
- Any concomitant medication within 2 weeks of the study.
- Difficult venous access
Key Trial Info
Start Date :
April 1 2009
Trial Type :
OBSERVATIONAL
Allocation :
ACTUAL
End Date :
July 1 2011
Estimated Enrollment :
21 Patients enrolled
Trial Details
Trial ID
NCT00884091
Start Date
April 1 2009
End Date
July 1 2011
Last Update
December 6 2011
Active Locations (1)
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1
Section of Endocrinology and Metabolism, Department of Medicine, Taipei Veterans General Hospital
Taipei, Taiwan, 112