Status:
COMPLETED
Magnetoencephalography in Absence Seizures
Lead Sponsor:
National Institute of Neurological Disorders and Stroke (NINDS)
Conditions:
Seizures
Eligibility:
All Genders
7-35 years
Brief Summary
Background: * An absence seizure is a type of seizure that usually begins in childhood and goes away by early adulthood. Scientists do not yet know where absence seizures begin in the brain. Some evi...
Detailed Description
Objective: This protocol will test the hypothesis that the 3-Hz spike-wave discharges seen in absence epilepsy originate in the thalamus. We will use an emerging modality, magnetoencephalograpy (MEG)...
Eligibility Criteria
Inclusion
- INCLUSION CRITERIA:
- Age 7-35
- Absence of seizures based on clinical and electroenecephalography data. Patients who have other seizure types (myoclonic, generalized tonic-clonic) in addition to absence seizures may be included.
- Patients who have other neurologic disorders may be included, as long as they are able to consent/assent.
- EXCLUSION CRITERIA:
- Contraindications to MEG studies (Dental braces, permanent retainers, metal dental caps/crowns/fillings)
- Contraindications to MRI studies (such as pacemakers, cochlear devices, surgical clips, metallic implants, orthopedic pins, shrapnel, permanent eyeliner, vagus nerve stimulator)
- Claustrophobia or anxiety disorders exacerbated by MRI
- Pregnancy
- Inability to provide consent/assent
Exclusion
Key Trial Info
Start Date :
April 15 2009
Trial Type :
OBSERVATIONAL
Allocation :
ACTUAL
End Date :
June 15 2011
Estimated Enrollment :
5 Patients enrolled
Trial Details
Trial ID
NCT00884351
Start Date
April 15 2009
End Date
June 15 2011
Last Update
July 2 2017
Active Locations (1)
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1
National Institutes of Health Clinical Center, 9000 Rockville Pike
Bethesda, Maryland, United States, 20892