Status:
COMPLETED
Efficacy of a Naturally-derived Mouthrinse for Gingival Inflammation
Lead Sponsor:
Shaare Zedek Medical Center
Conditions:
Gingivitis
Eligibility:
All Genders
14-75 years
Phase:
PHASE1
PHASE2
Brief Summary
Gingivitis, defined as inflammation of the gingival tissues, has long been associated with bacterial accumulation \[plaque\] on the tooth surface adjacent to the gingiva, causing an inflammatory react...
Eligibility Criteria
Inclusion
- Age 14-75.
- Clinical diagnosis of Gingivitis as measured by the Gingival index ≤ 0.5
- Healthy volunteer willing to cease all oral hygiene methods except for the mouthrinse for a period of three weeks.
- Have at least 24 teeth in their mouth
Exclusion
- Pregnant or planning to become pregnant during the study period.
- Periodontal pockets greater than 5mm in 3 or more areas.
- History of periodontal treatment within the last month.
- Antibiotic treatment within the last month
- Use of any antimicrobial mouthrinse within the last month.
- Participation in another trial within one month prior to the study.
- Inability to comply with the trial protocol by not rinsing with mouthrinse 20% of time.
- Inability to comply, brushing the teeth or using another mouthrinse during the study period.
- Systemic Disease.
- On antibiotic or anti-inflammatory medication
- Cigarette-smoking
Key Trial Info
Start Date :
June 1 2009
Trial Type :
INTERVENTIONAL
Allocation :
ACTUAL
End Date :
June 1 2010
Estimated Enrollment :
94 Patients enrolled
Trial Details
Trial ID
NCT00885599
Start Date
June 1 2009
End Date
June 1 2010
Last Update
July 17 2012
Active Locations (1)
Enter a location and click search to find clinical trials sorted by distance.
1
Shaare Zedek Medical Center
Jerusalem, Israel, 91031