Status:
COMPLETED
Effects of Dipeptidyl Peptidase-4 (DPP-4) Inhibition on Hormonal Responses to Macronutrient Ingestion
Lead Sponsor:
Lund University
Conditions:
Healthy
Type 2 Diabetes
Eligibility:
MALE
20-30 years
Phase:
PHASE4
Brief Summary
The regulation by DPP-4 inhibition after ingested of different individual macronutrients is not known. Therefore, this study examines the influence of ingestion of fat, protein, glucose or mixed meal ...
Detailed Description
Meal ingestion releases gut hormones which stimulate insulin secretion. A most important gut hormone is the incretin hormone glucagon-like peptide-1 (GLP-1). GLP-1 is rapidly degraded and inactivated ...
Eligibility Criteria
Inclusion
- Healthy men
- Age 20-30 years
- BMI 20-30 kg/m2
Exclusion
- Any disease
- Any medication
Key Trial Info
Start Date :
August 1 2009
Trial Type :
INTERVENTIONAL
Allocation :
ACTUAL
End Date :
September 1 2012
Estimated Enrollment :
12 Patients enrolled
Trial Details
Trial ID
NCT00885638
Start Date
August 1 2009
End Date
September 1 2012
Last Update
January 30 2014
Active Locations (1)
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1
Department of Clinical Sciences Lund, Lund University
Lund, Sweden, 221 84