Status:

COMPLETED

Influence of Muscle Relaxation on a Closed-loop Anesthesia System

Lead Sponsor:

Hopital Foch

Conditions:

Anesthesia, General

Eligibility:

All Genders

18+ years

Phase:

PHASE3

Brief Summary

Total intra-venous anesthesia can be provided using a closed-loop system guided by the bispectral index. The purpose of this study is to determine if myorelaxation modifies its functioning.

Eligibility Criteria

Inclusion

  • patients scheduled for a surgical procedure which not require a myorelaxation

Exclusion

  • age less than 18 years,
  • ASA III and above,
  • pregnant woman
  • combined general and regional anesthesia,
  • history of prolonged myorelaxation due to a decrease in cholinesterase,
  • patient with a known lack in cholinesterase,
  • history of cerebral or psychiatric central,
  • allergy to latex, propofol, remifentanil, morphine, muscle relaxant or any of the excipients,
  • known hypersensitivity to remifentanil or to an other derivative of fentanyl,
  • presence of a pacemaker,
  • psychotropic or agonist-antagonist morphine treatment,
  • planned post-operative sedation.

Key Trial Info

Start Date :

December 1 2009

Trial Type :

INTERVENTIONAL

Allocation :

ACTUAL

End Date :

February 1 2015

Estimated Enrollment :

140 Patients enrolled

Trial Details

Trial ID

NCT00886418

Start Date

December 1 2009

End Date

February 1 2015

Last Update

September 23 2016

Active Locations (3)

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Page 1 of 1 (3 locations)

1

CHU Besançon

Besançon, France, 25000

2

Institut Paoli-Calmette

Marseille, France, 13273

3

Hôpital Foch

Suresnes, France, 92151

Influence of Muscle Relaxation on a Closed-loop Anesthesia System | DecenTrialz