Status:

COMPLETED

Relapse Prevention Study Of Desvenlafaxine Succinate Sustained Release In Outpatients With Major Depressive Disorder

Lead Sponsor:

Pfizer

Conditions:

Major Depressive Disorder

Eligibility:

All Genders

18+ years

Phase:

PHASE3

Brief Summary

The primary purpose of this study is to compare the long-term efficacy and safety of desvenlafaxine succinate sustained release versus placebo in adults with Major Depressive Disorder, using a randomi...

Eligibility Criteria

Inclusion

  • Adult, outpatient with primary diagnosis of Major Depressive Disorder (depressive symptoms for at least 30 days prior to screening)
  • Hamilton Psychiatric Rating Scale for Depression (HAM-D 17) total score of \>= 20
  • Clinical Global Impressions Scale-Severity (CGI-S) score of \>= 4.

Exclusion

  • Significant risk of suicide as assessed by clinician judgment, HAM-D17 and Columbia Suicide-Severity Rating Scale scores.
  • Past treatment with desvenlafaxine succinate sustained release.
  • Other eligibility criteria also apply.

Key Trial Info

Start Date :

June 1 2009

Trial Type :

INTERVENTIONAL

Allocation :

ACTUAL

End Date :

March 1 2011

Estimated Enrollment :

874 Patients enrolled

Trial Details

Trial ID

NCT00887224

Start Date

June 1 2009

End Date

March 1 2011

Last Update

November 21 2014

Active Locations (90)

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Page 1 of 23 (90 locations)

1

Pfizer Investigational Site

Beverly Hills, California, United States, 90210

2

Pfizer Investigational Site

Encino, California, United States, 91316

3

Pfizer Investigational Site

Los Alamitos, California, United States, 90720

4

Pfizer Investigational Site

Orange, California, United States, 92868