Status:
COMPLETED
Prostacyclin's Effect on Platelet Responsiveness
Lead Sponsor:
Catholic University of the Sacred Heart
Conditions:
Acute Kidney Failure
Eligibility:
All Genders
20+ years
Phase:
PHASE4
Brief Summary
The researchers investigated the influence of a prostacyclin analogue (PGIA) versus unfractionated heparin (UFH) on ex vivo platelet function, during continuous venovenous hemodiafiltration.
Detailed Description
Context and purpose of the study: Prospective, randomized comparison of a PGIA versus UFH as circuit anticoagulant. Platelet responsiveness was assessed from peripheral blood by light-transmittance ag...
Eligibility Criteria
Inclusion
- critically patients ill patients with acute kidney failure (AKI) needing renal replacement therapy
Exclusion
- therapy with aspirin or other non-steroidal anti-inflammatory drugs in the previous 7 days
- concomitant treatment with other extracorporeal organ-assist devices any other drug affecting coagulation or platelets
Key Trial Info
Start Date :
September 1 2007
Trial Type :
INTERVENTIONAL
Allocation :
ACTUAL
End Date :
May 1 2008
Estimated Enrollment :
23 Patients enrolled
Trial Details
Trial ID
NCT00890214
Start Date
September 1 2007
End Date
May 1 2008
Last Update
April 29 2009
Active Locations (1)
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1
Policlinico Gemelli
Rome, Italy, 00168