Status:

COMPLETED

Should Any One Airway Clearance Technique be Recommended for People With Cystic Fibrosis?

Lead Sponsor:

Royal Brompton & Harefield NHS Foundation Trust

Conditions:

Cystic Fibrosis

Eligibility:

All Genders

16+ years

Phase:

PHASE4

Brief Summary

The study was to evaluate the long term effects, over one year, of five airway clearance techniques used by people with cystic fibrosis (active cycle of breathing techniques, autogenic drainage, posit...

Eligibility Criteria

Inclusion

  • Diagnosis of cystic fibrosis (genotype or sweat sodium concentration greater than 70 mmol/litre)
  • Forced expiratory volume in one second greater than or equal to 25% predicted, on assessment for entry to the study.

Exclusion

  • Evidence of a current respiratory exacerbation (Thornton et al 2004)
  • Current severe haemoptysis
  • Past history of pneumothorax
  • Awaiting lung / heart-lung transplantation
  • Pregnancy
  • Recent (within 3 months) acquisition of Burkholderia cepacia

Key Trial Info

Start Date :

July 1 1999

Trial Type :

INTERVENTIONAL

Allocation :

ACTUAL

End Date :

September 1 2003

Estimated Enrollment :

75 Patients enrolled

Trial Details

Trial ID

NCT00890370

Start Date

July 1 1999

End Date

September 1 2003

Last Update

April 29 2009

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