Status:

COMPLETED

Preoperative Intravenous Omega 3 Fatty Acids Administration in Valvular Surgery Patients

Lead Sponsor:

Nizam's Institute of Medical Sciences University, India

Conditions:

Valvular Surgery

Inflammation

Eligibility:

All Genders

18-50 years

Phase:

PHASE4

Brief Summary

The perioperative administration of n-3 fatty acids has been shown to lead to favorable effects on outcome in patients with severe surgical interventions by lowering the magnitude of inflammatory resp...

Eligibility Criteria

Inclusion

  • Adult male or female patients undergoing valvular surgeries
  • Age 18-50 years
  • The patients who give written informed consent

Exclusion

  • Refusal to participate in the study
  • Allergy to any of the constituents of nutritional products
  • HIV positive patients, patients with primary diagnosis of hypertriglyceridemia, patients on long term steroid therapy and cycloxygenase inhibitors (more than 3 months)
  • Severe cardiac disease, hepatic disorders (total bilirubin \> 1.5 times the upper limit of normal), psychiatric disorders likely to affect compliance, severe hemorrhagic disorders, stroke, embolism
  • Uncontrolled severe renal failure (Serum creatinine \> 2 mg/dL) without dialysis/hemofiltration
  • Pregnant or nursing women
  • Participation in any other clinical trial within the last 2 months

Key Trial Info

Start Date :

April 1 2009

Trial Type :

INTERVENTIONAL

Allocation :

ACTUAL

End Date :

December 1 2010

Estimated Enrollment :

40 Patients enrolled

Trial Details

Trial ID

NCT00890838

Start Date

April 1 2009

End Date

December 1 2010

Last Update

October 2 2014

Active Locations (1)

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NIzam's Institute of Medical Sciences

Hyderabad, Andhra Pradesh, India