Status:

COMPLETED

Can Treatment With Bismuth Reduce Toxicity to Chemotherapy and Radiotherapy?

Lead Sponsor:

Copenhagen University Hospital at Herlev

Conditions:

Hematological Diseases

Hematological Malignancies

Eligibility:

All Genders

18-75 years

Phase:

NA

Brief Summary

The purpose of this study is to determine whether treatment with Bismuth can reduce the toxicity of chemotherapy and radiotherapy in patients with malignant diseases of the blood.

Eligibility Criteria

Inclusion

  • Patients of 18 years or over referred to the Department of Haematology L, Herlev Hospital, with a view to 'cytostatic'? treatment of or radiotherapy for haematological malignancy

Exclusion

  • Pregnant women and nursing mothers
  • No informed consent from patient
  • Known hyper sensitivity to bismuth or other tablet content
  • Severe renal insufficiency with creatinin clearance below 25 ml/min.
  • Patients receiving other treatment for protection of the mucous membrane except cryo treatment of the oral cavity (lumps of ice in the mouth)
  • Other experimental treatment within past four weeks.

Key Trial Info

Start Date :

May 1 2009

Trial Type :

INTERVENTIONAL

Allocation :

ACTUAL

End Date :

February 1 2013

Estimated Enrollment :

50 Patients enrolled

Trial Details

Trial ID

NCT00892502

Start Date

May 1 2009

End Date

February 1 2013

Last Update

September 10 2013

Active Locations (1)

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1

Department of Haematology L, Herlev Hospital, Herlev Ringvej 75

Herlev, Denmark, DK-2650