Status:
UNKNOWN
Magnetoencephalographic (MEG) Correlates of Negative Symptoms in Patients Suffering From Schizophrenia and Their Influence by Add-on Treatments
Lead Sponsor:
Shalvata Mental Health Center
Collaborating Sponsors:
Bar-Ilan University, Israel
Conditions:
Schizophrenia
Eligibility:
All Genders
18-65 years
Brief Summary
The objective of the suggested study is to identify changes in MEG correlates caused by the add-on treatment with the changes in negative symptoms of schizophrenia by comparing the change in the MEG c...
Detailed Description
There is a paucity of information regarding electrophysiological correlates of negative symptoms in patients suffering from schizophrenia. The proposed study is set out to compare the MEG correlates o...
Eligibility Criteria
Inclusion
- Study Group (Schizophrenia Patients) Inclusion Criteria
- Patients between the ages of 18-65 (male and female), Diagnosed in the past as suffering from schizophrenia. The diagnosis will be reaffirmed according to ICD criteria.
- Right hand dominant.
- Scores in PANSS negative questionnaire above 21 and positive symptom less than 24.
- Gave informed consent for participation in the study.
- Stable on the same antipsychotic medication for at least a month prior to entering the study Control Group (healthy Subjects)
- Inclusion criteria:
- Healthy man and woman
- Ages 18-65
- Right handed
Exclusion
- Study Group (Schizophrenia Patients) (To prevent MEG artifacts by non relevant electric interference or brain conditions)
- History of epilepsy, seizure, or hot spasm, sever head injuries.
- History of metal in the head (outside the mouth space).
- History of surgery including metal implant or history of metal particles in the eye, pacemaker, or any other medical pump.
- History of migraines.
- History of drug or alcohol abuse during the last year. Inability to achieve satisfying level of communication with the subject Control Group (healthy Subjects)
- History of psychiatric diagnosis
- Drug or alcohol addiction in the year prior to the study
- History of epilepsy, seizure, or hot spasm.
- History of head injuries.
- History of metal in the head (outside the mouth space).
- History of surgery including metal implant or history of metal particles in the eye, pacemaker, or any other medical pump.
- History of migraines.
- Use of psychotropic medication
Key Trial Info
Start Date :
March 1 2009
Trial Type :
OBSERVATIONAL
Allocation :
ESTIMATED
End Date :
January 1 2013
Estimated Enrollment :
50 Patients enrolled
Trial Details
Trial ID
NCT00894296
Start Date
March 1 2009
End Date
January 1 2013
Last Update
January 5 2012
Active Locations (1)
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1
Bar-Ilan University
Givat Shmuel, Israel