Status:
COMPLETED
Neuromuscular Blockade Improves Surgical Conditions
Lead Sponsor:
Technical University of Munich
Conditions:
Neuromuscular Blockade
Eligibility:
All Genders
18-64 years
Phase:
NA
Brief Summary
This study is designed to test the clinical hypothesis that a neuromuscular block improves surgical conditions, operation time, and post-operative pain.
Detailed Description
Muscle relaxants are part of a balanced anesthesia regimen. So far, evidence is given that a neuromuscular block improves intubating conditions and protects against laryngeal morbidity. The doctrine, ...
Eligibility Criteria
Inclusion
- Patients scheduled for elective laparoscopic cholecystectomy under general anesthesia
- Patients ASA physical status I - III
- Patients between 18 and 64 years
- Patients scheduled for general anesthesia with intubation using rocuronium
- Patients having given informed consent to the study
Exclusion
- Anatomic and functional malformations with expected difficult intubation
- Known or suspected neuromuscular disease
- Significant hepatic or renal dysfunction
- Known or suspected history or family history of disposition to malignant hyperthermia
- Known or suspected allergy towards sugammadex, anesthetics, muscle relaxants, or other drugs used for general anesthesia
- Use of drugs that interfere with muscle relaxants
- Patients, included in another trial within the last 30 days
- Patients, with legal guidant
- Patients with contraindication towards the use of Sugammadex, neostigmine or glycopyrrolate
- Patients, which have already participated in a sugammadex trial
- Pregnant women (exclusion of pregnancy: postmenopausal status, negative beta-HCG screen, status post tubal ligation)
- Breastfeeding women
- Patients who are unable to understand or successfully administer a patient- controlled-analgesia (PCA) device
Key Trial Info
Start Date :
March 1 2009
Trial Type :
INTERVENTIONAL
Allocation :
ACTUAL
End Date :
December 1 2012
Estimated Enrollment :
57 Patients enrolled
Trial Details
Trial ID
NCT00895778
Start Date
March 1 2009
End Date
December 1 2012
Last Update
March 19 2013
Active Locations (1)
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1
Klinik für Anaesthesiologie, Klinikum rechts der Isar der Technischen Universität München
Munich, Bavaria, Germany, 81675