Status:
TERMINATED
Gene Function in Bone Marrow Cells From Patients With Fanconi Anemia and From Healthy Participants
Lead Sponsor:
OHSU Knight Cancer Institute
Collaborating Sponsors:
National Cancer Institute (NCI)
Conditions:
Fanconi Anemia
Eligibility:
All Genders
1-55 years
Brief Summary
RATIONALE: Studying samples of bone marrow from patients with Fanconi anemia and from healthy participants in the laboratory may help doctors learn more about changes that occur in DNA and identify bi...
Detailed Description
OBJECTIVES: * Describe the complete hematopoietic transcriptomes of Fanconi cells of every common complementation group (e.g., A, C, G, and F) as well as transcriptomes of neoplastic cells derived fr...
Eligibility Criteria
Inclusion
- DISEASE CHARACTERISTICS:
- Meets 1 of the following criteria:
- Diagnosis of Fanconi anemia
- Requires bone marrow aspiration or biopsy for clinical purposes
- Healthy volunteer
- Over 18 years of age
- No known blood abnormality
- PATIENT CHARACTERISTICS:
- Platelet count \> 150,000/mm\^3
- White Blood Cell(WBC) \> 4,000/mm\^3
- Hemoglobin \> 13 g/dL
- No clinical signs or symptoms of acute or subacute infection (e.g., viral, bacterial, or fungal)
- No allergies to lidocaine or xylocaine
- PRIOR CONCURRENT THERAPY:
- Not specified
Exclusion
Key Trial Info
Start Date :
March 1 2002
Trial Type :
OBSERVATIONAL
Allocation :
ACTUAL
End Date :
September 1 2007
Estimated Enrollment :
90 Patients enrolled
Trial Details
Trial ID
NCT00896740
Start Date
March 1 2002
End Date
September 1 2007
Last Update
December 4 2017
Active Locations (1)
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1
Knight Cancer Institute at Oregon Health and Science University
Portland, Oregon, United States, 97239-3098