Status:

COMPLETED

Gene Expression Profiles to Categorize Wilms Tumors

Lead Sponsor:

Children's Oncology Group

Collaborating Sponsors:

National Cancer Institute (NCI)

Conditions:

Recurrent Wilms Tumor and Other Childhood Kidney Tumors

Stage I Wilms Tumor

Eligibility:

All Genders

Brief Summary

This laboratory study is using gene expression profiling to identify different categories of Wilms tumors. Studying the genes expressed in samples of tumor tissue from patients with cancer may help do...

Detailed Description

OBJECTIVES: I. Identify new molecular categories of Wilms tumor (WT) based on the gene expression profiles of samples from patients with this disease. II. Develop a classifying system (classifier) t...

Eligibility Criteria

Inclusion

  • Inclusion Criteria:
  • Specimens from patients previously enrolled as "On Study" or "Followed Biology Only" on protocol NWTSG-5 (COG-Q9401)
  • Study follow-up data for disease status available
  • National Wilms Tumor Study Group/Children's Oncology Group pathology review showing "favorable" histology
  • Sufficient biology samples available without using biology bank reserves

Exclusion

    Key Trial Info

    Start Date :

    February 1 2004

    Trial Type :

    OBSERVATIONAL

    Allocation :

    ACTUAL

    End Date :

    Estimated Enrollment :

    600 Patients enrolled

    Trial Details

    Trial ID

    NCT00897637

    Start Date

    February 1 2004

    Last Update

    May 19 2016

    Active Locations (2)

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    Page 1 of 1 (2 locations)

    1

    Children's Oncology Group

    Arcadia, California, United States, 91006-3776

    2

    Saint Mary's Hospital

    West Palm Beach, Florida, United States, 33407