Status:
UNKNOWN
Evaluating the Side Effects and How Well Anticancer Drugs Work in Very Young Patients With Cancer
Lead Sponsor:
Children's Cancer and Leukaemia Group
Conditions:
Unspecified Childhood Solid Tumor, Protocol Specific
Eligibility:
All Genders
Up to 2 years
Brief Summary
RATIONALE: Studying samples of blood in the laboratory from young patients with cancer may help doctors learn how carboplatin, cyclophosphamide, and etoposide affect the body and how patients will res...
Detailed Description
OBJECTIVES: * Investigate inter-individual variability in the pharmacokinetics of selected anticancer drugs in infants and children age \< 2 years on current dosing schedules. * Compare drug exposure...
Eligibility Criteria
Inclusion
- DISEASE CHARACTERISTICS:
- Diagnosis of childhood cancer
- Receiving carboplatin, cyclophosphamide, or etoposide as standard treatment as part of a clinical study at a Children's Cancer and Leukemia Group (CCLG) center
- PATIENT CHARACTERISTICS:
- Not specified
- PRIOR CONCURRENT THERAPY:
- Single or double lumen central venous catheter in place
- No concurrent anticonvulsants, azole antifungal agents, or chronic steroid treatment
Exclusion
Key Trial Info
Start Date :
February 1 2007
Trial Type :
OBSERVATIONAL
Allocation :
ESTIMATED
End Date :
Estimated Enrollment :
60 Patients enrolled
Trial Details
Trial ID
NCT00897871
Start Date
February 1 2007
Last Update
August 12 2013
Active Locations (21)
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1
Our Lady's Hospital for Sick Children Crumlin
Dublin, Ireland, 12
2
Birmingham Children's Hospital
Birmingham, England, United Kingdom, B4 6NH
3
Bristol Royal Hospital for Children
Bristol, England, United Kingdom, BS2 8BJ
4
Addenbrooke's Hospital
Cambridge, England, United Kingdom, CB2 2QQ