Status:

COMPLETED

S9431: Studying Genes and Immune Response in Tumor Samples From Patients With Locally Advanced or Metastatic Melanoma

Lead Sponsor:

SWOG Cancer Research Network

Collaborating Sponsors:

National Cancer Institute (NCI)

Eastern Cooperative Oncology Group

Conditions:

Melanoma (Skin)

Eligibility:

All Genders

18+ years

Brief Summary

RATIONALE: Studying samples of tumor tissue and blood from patients with cancer in the laboratory may help doctors learn more about changes that occur in DNA and identify biomarkers related to cancer....

Detailed Description

OBJECTIVES: * Characterize the frequency of non-random cytogenetic abnormalities in regional and distant melanoma metastases and explore their association with clinical outcome of patients with metas...

Eligibility Criteria

Inclusion

  • DISEASE CHARACTERISTICS:
  • Diagnosis of stage III or IV metastatic melanoma
  • Concurrent enrollment on a SWOG-coordinated melanoma treatment study (within 56 days of registration on this study) OR
  • Previously enrolled on and eligible for at least 1 SWOG-coordinated melanoma study and scheduled to undergo biopsy/surgery for regional lymph node or disseminated metastatic disease OR
  • Concurrent enrollment on SWOG-9430 (FISH analysis)
  • PATIENT CHARACTERISTICS:
  • Age
  • Not specified
  • Performance status
  • Not specified
  • Life expectancy
  • Not specified
  • Hematopoietic
  • Not specified
  • Hepatic
  • Not specified
  • Renal
  • Not specified
  • PRIOR CONCURRENT THERAPY:
  • Biologic therapy
  • Not specified
  • Chemotherapy
  • Not specified
  • Endocrine therapy
  • Not specified
  • Radiotherapy
  • Not specified
  • Surgery
  • Not specified
  • Other
  • Not previously enrolled on SWOG-9431

Exclusion

    Key Trial Info

    Start Date :

    November 1 1996

    Trial Type :

    OBSERVATIONAL

    Allocation :

    ACTUAL

    End Date :

    February 1 2007

    Estimated Enrollment :

    91 Patients enrolled

    Trial Details

    Trial ID

    NCT00898183

    Start Date

    November 1 1996

    End Date

    February 1 2007

    Last Update

    June 28 2018

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