Status:

COMPLETED

Identifying Risk Factors for Bone Tissue Death in Young Patients With Acute Lymphoblastic Leukemia Treated on Clinical Trial CCG-1882

Lead Sponsor:

Children's Oncology Group

Collaborating Sponsors:

National Cancer Institute (NCI)

Conditions:

Leukemia

Eligibility:

All Genders

10-120 years

Brief Summary

RATIONALE: Studying samples of tissue from patients with cancer in the laboratory may help doctors learn more about changes that occur in DNA and identify biomarkers related to bone tissue death. PUR...

Detailed Description

OBJECTIVES: * Identify possible pharmacogenetic risk factors for avascular necrosis (AVN) in pediatric patients who received intensive therapy for acute lymphoblastic leukemia on clinical trial CCG-1...

Eligibility Criteria

Inclusion

  • DISEASE CHARACTERISTICS:
  • Diagnosis of acute lymphoblastic leukemia (ALL)
  • Has diagnostic ALL blast sample slides available for DNA extraction
  • Previously treated on clinical trial CCG-1882
  • PATIENT CHARACTERISTICS:
  • Age
  • 10 and over at diagnosis
  • Performance status
  • Not specified
  • Life expectancy
  • Not specified
  • Hematopoietic
  • Not specified
  • Hepatic
  • Not specified
  • Renal
  • Not specified
  • PRIOR CONCURRENT THERAPY:
  • Biologic therapy
  • Not specified
  • Chemotherapy
  • Not specified
  • Endocrine therapy
  • Not specified
  • Radiotherapy
  • Not specified
  • Surgery
  • Not specified

Exclusion

    Key Trial Info

    Start Date :

    March 1 2005

    Trial Type :

    OBSERVATIONAL

    Allocation :

    ESTIMATED

    End Date :

    May 1 2016

    Estimated Enrollment :

    671 Patients enrolled

    Trial Details

    Trial ID

    NCT00898469

    Start Date

    March 1 2005

    End Date

    May 1 2016

    Last Update

    May 11 2016

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