Status:

COMPLETED

Genes in Predicting Outcome in Patients With Esophageal Cancer Treated With Cisplatin, Radiation Therapy, and Surgery

Lead Sponsor:

ECOG-ACRIN Cancer Research Group

Collaborating Sponsors:

National Cancer Institute (NCI)

Conditions:

Esophageal Cancer

Eligibility:

All Genders

18-120 years

Brief Summary

RATIONALE: Studying samples of tissue in the laboratory from patients with cancer may help doctors learn more about changes that occur in DNA and identify biomarkers related to cancer. It may also hel...

Detailed Description

OBJECTIVES: * Correlate patient outcomes with neoplastic cell genotypes, specifically 18 single nucleotide polymorphisms (SNPs) in 16 major genes involved in platinum metabolism and disposition and D...

Eligibility Criteria

Inclusion

  • DISEASE CHARACTERISTICS:
  • Diagnosis of adenocarcinoma of the esophagus
  • Stage I-IV disease
  • Received cisplatin-based treatment on clinical trial ECOG-1201
  • PATIENT CHARACTERISTICS:
  • Not specified
  • PRIOR CONCURRENT THERAPY:
  • Not specified

Exclusion

    Key Trial Info

    Start Date :

    May 11 2007

    Trial Type :

    OBSERVATIONAL

    Allocation :

    ACTUAL

    End Date :

    December 31 2008

    Estimated Enrollment :

    118 Patients enrolled

    Trial Details

    Trial ID

    NCT00898495

    Start Date

    May 11 2007

    End Date

    December 31 2008

    Last Update

    July 31 2020

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