Decentrialz logo
  • HIPAA Compliant
  • ISO 27001 Certified
Find Trials
About UsContact
Become a Volunteer+1 877 705 1914

Status:

COMPLETED

Prebiotics and Immune Function in Middle Aged Humans

Lead Sponsor:

University Hospital Southampton NHS Foundation Trust

Collaborating Sponsors:

University of Southampton

Conditions:

Immune Function

Eligibility:

All Genders

45-66 years

Phase:

PHASE1

PHASE2

Brief Summary

Prebiotics are naturally occurring carbohydrates found in a variety of edible plants. They are not digested by mammalian enzymes, and so reach the gut intact, where they are fermented by some species ...

Detailed Description

Prebiotics are naturally occurring carbohydrates found in a variety of edible plants. They are not digested by mammalian enzymes, and so reach the gut intact, where they are fermented by some species ...

Eligibility Criteria

Inclusion

  • Aged 45-65 years
  • Body mass index 20 to 32 kg/m2.
  • Not consuming probiotic supplements, yoghurts, drinks or other foods
  • Not consuming prebiotic supplemented drinks or foods
  • In general good health
  • No antibiotic use in the 2 months prior to entering the study or during the study
  • Not been vaccinated with the current season's influenza vaccine
  • Being able to provide written informed consent

Exclusion

  • Aged \< 45 or \> 66 years
  • Body mass index \< 20 or \> 32 kg/m2.
  • Being diabetic (type 1 or type 2)
  • Displaying manifestations of allergy - asthma, hay-fever, dermatitis - or being treated for these
  • Being egg allergic
  • Use of any prescribed medicine (unless deemed to be acceptable by the PI)
  • Suffering from any infectious illness
  • Chronic gastrointestinal problems (e.g. IBD, IBS, cancer)
  • Recent blood donation
  • Participation in another clinical trial
  • Use of prebiotic or probiotic supplements, foods or drinks
  • Consuming vitamin, mineral or oil supplements
  • Previously vaccinated with the influenza vaccine being used.

Key Trial Info

Start Date :

April 1 2009

Trial Type :

INTERVENTIONAL

Allocation :

ACTUAL

End Date :

July 1 2010

Estimated Enrollment :

49 Patients enrolled

Trial Details

Trial ID

NCT00898599

Start Date

April 1 2009

End Date

July 1 2010

Last Update

December 2 2014

Active Locations (1)

Enter a location and click search to find clinical trials sorted by distance.

Page 1 of 1 (1 locations)

1

University of Southampton

Southampton, United Kingdom, SO16 6YD