Status:
COMPLETED
Collecting and Storing Tissue From Young Patients With Cancer
Lead Sponsor:
Children's Oncology Group
Collaborating Sponsors:
National Cancer Institute (NCI)
Conditions:
Acute Lymphoblastic Leukemia
Acute Myeloid Leukemia
Eligibility:
All Genders
Up to 21 years
Brief Summary
This laboratory study is collecting and storing tissue, blood, and bone marrow samples from young patients with cancer. Collecting and storing samples of tissue, blood, and bone marrow from patients w...
Detailed Description
PRIMARY OBJECTIVES: I. Establish and bank cell lines and/or xenografts from pediatric patients with cancer. II. Establish continuous cell lines, under carefully controlled conditions, from pediatric...
Eligibility Criteria
Inclusion
- Inclusion Criteria:
- All malignant tissues from childhood cancers allowed including the following:
- Brain tumors (all types)
- Tissue should be submitted to CNS Committee Resource labs to be forwarded for this study, unless instructed otherwise on the COG web site
- Ewing family of tumors
- Rhabdomyosarcomas
- Other soft tissue sarcomas
- Osteogenic sarcomas
- Rhabdoid tumors
- Neuroblastomas
- Viable material for cell culture for neuroblastoma is collected via COG-ANBL00B1 and should not be submitted via this study unless the patient cannot be enrolled on COG-ANBL00B1\*
- Retinoblastomas
- Anaplastic Wilms tumor
- Germ cell tumors
- Leukemias/lymphomas
- Acute myeloid leukemia (AML)
- Blood samples and bone marrow samples from patients at second relapse and beyond may be submitted for this study
- Bone marrow samples at diagnosis or first relapse must be submitted to an AML resource lab and will be forwarded for this study at the discretion of the AML Committee
- Acute lymphoblastic leukemia (ALL)
- Blood samples may be submitted directly to this study
- Bone marrow samples must be submitted to an ALL resource lab and will be forwarded for this study at the discretion of the ALL Committee
- Enrolled on a COG therapeutic, biology, or tissue banking protocol that allows collection of tissue for research and submission to a COG-designated resource laboratory
- Participation in this protocol is not permitted until after tissue requirements for any active COG disease-specific therapeutic, biology, or banking protocols have been satisfied
- Material may only be submitted for this protocol if tissue is available in excess of that required for satisfying active disease-specific therapeutic and biological protocols
- Patients with diagnosis pending are eligible
Exclusion
Key Trial Info
Start Date :
March 5 2007
Trial Type :
OBSERVATIONAL
Allocation :
ESTIMATED
End Date :
March 31 2025
Estimated Enrollment :
213 Patients enrolled
Trial Details
Trial ID
NCT00898755
Start Date
March 5 2007
End Date
March 31 2025
Last Update
May 2 2025
Active Locations (68)
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1
Children's Hospital of Alabama
Birmingham, Alabama, United States, 35233
2
University of Alabama at Birmingham Cancer Center
Birmingham, Alabama, United States, 35233
3
Arkansas Children's Hospital
Little Rock, Arkansas, United States, 72202-3591
4
University of Arkansas for Medical Sciences
Little Rock, Arkansas, United States, 72205