Status:
WITHDRAWN
Breast Cancer Risk in Women Who Are BRCA1/BRCA2 Mutation Carriers
Lead Sponsor:
Gynecologic Oncology Group
Collaborating Sponsors:
National Cancer Institute (NCI)
Conditions:
BRCA1 Mutation Carrier
BRCA2 Mutation Carrier
Eligibility:
FEMALE
18-80 years
Brief Summary
This research study is looking at breast cancer risk in women who are BRCA1/BRCA2 mutation carriers. Studying samples of DNA in the laboratory from women who are BRCA1/BRCA2 mutation carriers may help...
Detailed Description
OBJECTIVE: I. To identify potential genetic modifiers of breast cancer risk in women who are carriers of the breast cancer susceptibility genes, BRCA1/2, by collecting data and genetic information fr...
Eligibility Criteria
Inclusion
- Inclusion Criteria:
- Women with or without a personal history of breast cancer prior to enrollment in Gynecologic Oncology Group (GOG)-0199
- Known currently to be BRCA1/2 mutation carrier either by confirmed outside report or by research testing
- No BRCA1/2 mutation-negative or mutation-unknown status
- Enrolled on clinical trial GOG-0199 AND meets the following criteria:
- Completed baseline questionnaire (BQ-199)
- Provided information on previous breast cancer history, including date of diagnosis
- Provided complete data from the DNA analysis on the genetic variants of interest
- Available DNA samples for analysis
- Hormone receptor status not specified
- Pre- or post-menopausal status
Exclusion
Key Trial Info
Start Date :
May 1 2008
Trial Type :
OBSERVATIONAL
Allocation :
ACTUAL
End Date :
Estimated Enrollment :
Patients enrolled
Trial Details
Trial ID
NCT00899145
Start Date
May 1 2008
Last Update
July 13 2017
Active Locations (1)
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1
Gynecologic Oncology Group
Philadelphia, Pennsylvania, United States, 19103