Status:
COMPLETED
S9333A Study of Blood and Bone Marrow Samples From Patients With Previously Untreated Primary Acute Myeloid Leukemia
Lead Sponsor:
SWOG Cancer Research Network
Collaborating Sponsors:
National Cancer Institute (NCI)
Conditions:
Leukemia
Eligibility:
All Genders
56+ years
Brief Summary
RATIONALE: Studying samples of blood and bone marrow from patients with cancer in the laboratory may help doctors learn more about changes that occur in DNA and identify biomarkers related to cancer. ...
Detailed Description
OBJECTIVES: * Determine whether calmodulin-dependent protein kinase II-γ (CaMKIIγ) activation (autophosphorylation) is associated with specific clinicopathological variables and outcomes in blood and...
Eligibility Criteria
Inclusion
- DISEASE CHARACTERISTICS:
- Cryopreserved specimens of marrow or peripheral blood from patients enrolled in clinical trial SWOG-9333 and meeting the following criteria:
- Diagnosis of primary acute myeloid leukemia
- No M3 disease
- Previously untreated disease
- Randomized to remission induction chemotherapy with mitoxantrone hydrochloride and etoposide (Arm II)
- PATIENT CHARACTERISTICS:
- Not specified
- PRIOR CONCURRENT THERAPY:
- See Disease Characteristics
Exclusion
Key Trial Info
Start Date :
August 1 2008
Trial Type :
OBSERVATIONAL
Allocation :
ACTUAL
End Date :
June 1 2009
Estimated Enrollment :
132 Patients enrolled
Trial Details
Trial ID
NCT00899743
Start Date
August 1 2008
End Date
June 1 2009
Last Update
March 6 2015
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