Status:

WITHDRAWN

Cyclooxygenase-2 Expression in Tissue Samples From Patients With a Normal Cervix, Cervical Intraepithelial Neoplasia, or Early Invasive Cervical Cancer

Lead Sponsor:

Wake Forest University Health Sciences

Collaborating Sponsors:

National Cancer Institute (NCI)

Conditions:

Cervical Cancer

Precancerous Condition

Eligibility:

FEMALE

18-120 years

Brief Summary

RATIONALE: Studying samples of tissue from patients with or without cancer in the laboratory may help doctors identify and learn more about biomarkers related to cancer. PURPOSE: This laboratory stud...

Detailed Description

OBJECTIVES: * Determine cyclooxygenase-2 (COX-2) levels in biopsy or surgical specimens from patients with normal cervical epithelium, cervical intraepithelial neoplasia, or microinvasive squamous ce...

Eligibility Criteria

Inclusion

  • DISEASE CHARACTERISTICS:
  • Meets 1 of the following criteria:
  • Underwent hysterectomy with removal of a normal cervix for diagnosis unrelated to cancer or cervical dysplasia
  • Underwent cervical biopsy or removal of cervical tissue and diagnosed with cervical intraepithelial neoplasia (CIN) grades 1-3
  • Underwent cervical biopsy and diagnosed with microinvasive squamous cell carcinoma of the cervix
  • Paraffin-embedded tissue samples of normal cervical epithelium, CIN, or microinvasive squamous cell carcinoma of the cervix must be available for examination
  • PATIENT CHARACTERISTICS:
  • Not specified
  • PRIOR CONCURRENT THERAPY:
  • Not specified

Exclusion

    Key Trial Info

    Start Date :

    May 1 2003

    Trial Type :

    OBSERVATIONAL

    Allocation :

    ACTUAL

    End Date :

    May 1 2003

    Estimated Enrollment :

    Patients enrolled

    Trial Details

    Trial ID

    NCT00900081

    Start Date

    May 1 2003

    End Date

    May 1 2003

    Last Update

    August 1 2017

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