Status:
COMPLETED
Biomarkers in Patients With Kidney Cancer or Cancer of the Urothelium and in Healthy Participants
Lead Sponsor:
Wake Forest University Health Sciences
Collaborating Sponsors:
National Cancer Institute (NCI)
Conditions:
Bladder Cancer
Kidney Cancer
Eligibility:
All Genders
18-120 years
Brief Summary
RATIONALE: Studying samples of blood and urine from patients with cancer and from healthy participants in the laboratory may help doctors identify and learn more about biomarkers related to cancer. P...
Detailed Description
OBJECTIVES: * Determine whether bone morphogenetic protein antagonist regulated in cancer (BARC) is present in urine and serum samples from patients with renal cell carcinoma or transitional cell car...
Eligibility Criteria
Inclusion
- Inclusion:
- Age \> 18 years
- Meets 1 of the following criteria:
- Diagnosis of renal cell carcinoma, meeting all of the following criteria:
- Suitable surgical candidate
- No clinical or pathologic T stage \> T2
- No clinical or pathologic evidence of vein and/or lymph node involvement
- No evidence of metastatic disease as evaluated by abdominal/pelvic CT scan or MRI, chest x-ray or chest CT scan, and bone scan (if alkaline phosphatase abnormal)
- Diagnosis of transitional cell carcinoma of the urothelium
- Currently undergoing Bacille calmette-guérin (BCG) therapy OR has not received prior BCG therapy
- Healthy participant (control)
- No history of carcinoma
- Exclusion:
- Previous or concurrent malignancy except curatively treated carcinoma in situ of the cervix or nonmelanoma skin cancer
- Serious medical or psychiatric illness that would preclude study compliance
- Current participation in a treatment related research study within the last 30 days
- Acute illness
- Bleeding disorder or dyscrasia
Exclusion
Key Trial Info
Start Date :
June 1 2006
Trial Type :
OBSERVATIONAL
Allocation :
ACTUAL
End Date :
April 1 2011
Estimated Enrollment :
5 Patients enrolled
Trial Details
Trial ID
NCT00900276
Start Date
June 1 2006
End Date
April 1 2011
Last Update
July 5 2018
Active Locations (1)
Enter a location and click search to find clinical trials sorted by distance.
1
Wake Forest University Comprehensive Cancer Center
Winston-Salem, North Carolina, United States, 27157-1096