Status:

COMPLETED

OX-40 Protein Expression in the Sentinel Lymph Nodes of Patients With Cancer

Lead Sponsor:

OHSU Knight Cancer Institute

Collaborating Sponsors:

National Cancer Institute (NCI)

Conditions:

Cancer

Eligibility:

All Genders

Up to 120 years

Brief Summary

RATIONALE: Studying protein expression in sentinel lymph node tissue from patients with cancer in the laboratory may help doctors identify and learn more about biomarkers related to cancer. It may als...

Detailed Description

OBJECTIVES: * Determine the qualitative and quantitative expression of OX-40 and related markers in sentinel lymph nodes previously removed from patients with cancer. * Determine the qualitative and ...

Eligibility Criteria

Inclusion

  • DISEASE CHARACTERISTICS:
  • Histologically or cytologically confirmed cancer, including, but not limited to, the following:
  • Melanoma
  • Breast cancer
  • Invasive squamous cell cancer
  • Other cancers for which patients underwent or will undergo the following:
  • Adequate archived paraffin-embedded tissue for making slides for immunostaining
  • Adequate freshly removed sentinel lymph node (and primary tumor, if available) tissue for laboratory assays
  • Clinical data and date of last follow-up on tumor stage and status must be available
  • Hormone receptor status not specified
  • PATIENT CHARACTERISTICS:
  • Not specified
  • PRIOR CONCURRENT THERAPY:
  • Not specified

Exclusion

    Key Trial Info

    Start Date :

    April 1 2005

    Trial Type :

    OBSERVATIONAL

    Allocation :

    ACTUAL

    End Date :

    March 1 2011

    Estimated Enrollment :

    98 Patients enrolled

    Trial Details

    Trial ID

    NCT00900302

    Start Date

    April 1 2005

    End Date

    March 1 2011

    Last Update

    February 10 2016

    Active Locations (1)

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    OHSU Knight Cancer Institute

    Portland, Oregon, United States, 97239-3098