Status:
COMPLETED
Association Between Perioperative Platelet Function and Major Adverse Perioperative Events
Lead Sponsor:
Hamilton Health Sciences Corporation
Collaborating Sponsors:
University Health Network, Toronto
London Health Sciences Centre
Conditions:
Surgery
Eligibility:
All Genders
30-85 years
Brief Summary
This study will examine the degree of blood thinning (platelet function) in patients coming for non-cardiac surgery on antiplatelet agents using platelet function tests called thromboelastography (TEG...
Detailed Description
Patients who have had stents in their coronary arteries (PCI) have to stay on antiplatelet agents to prevent clotting of their stents. These patients often require non-cardiac surgery (NCS) at some st...
Eligibility Criteria
Inclusion
- patients between ages 30-85 years old, receiving post-PCI aspirin and/or clopidogrel therapy
- patients undergoing non-ambulatory, NCS
- patients will have received a bare metal coronary stent within the last 12 months or a drug eluting stent at any time prior to their NCS
- the type of surgery has to be such that there are no contra-indictions to remain on an anti-platelet agent
- surgeon must agree to keep the patient on at least one anti-platelet agent during the perioperative period
Exclusion
- clotting abnormalities
- drugs affecting platelet function other than aspirin or clopidogrel
- moderate renal impairment
- liver dysfunction with co-existing thrombocytopenia
Key Trial Info
Start Date :
March 1 2009
Trial Type :
OBSERVATIONAL
Allocation :
ACTUAL
End Date :
September 1 2015
Estimated Enrollment :
250 Patients enrolled
Trial Details
Trial ID
NCT00901030
Start Date
March 1 2009
End Date
September 1 2015
Last Update
September 23 2015
Active Locations (3)
Enter a location and click search to find clinical trials sorted by distance.
1
Hamilton Health Sciences
Hamilton, Ontario, Canada, L8L 2X2
2
London Health Sciences Centre
London, Ontario, Canada, N6A 5A5
3
University Health Network
Toronto, Ontario, Canada, M5G 2C4