Status:
COMPLETED
Intra-arterial Chemotherapy(Chemosurgery) for Retinoblastoma
Lead Sponsor:
Weill Medical College of Cornell University
Collaborating Sponsors:
Memorial Sloan Kettering Cancer Center
Conditions:
Retinoblastoma
Eligibility:
All Genders
1+ years
Phase:
PHASE1
PHASE2
Brief Summary
Conventional treatments of retinoblastoma involves laser photocoagulation, cryotherapy (freezing of the tumor), plaque radiotherapy,external beam radiotherapy, and intravenous chemotherapy. Enucleatio...
Detailed Description
Present treatments for intraocular retinoblastoma cure 99% of children but have significant toxicity. Enucleation of the eye is effective but blinds the eye and leaves a lifelong cosmetic deformity. R...
Eligibility Criteria
Inclusion
- advanced retinoblastoma in one or both eyes
- recurrent retinoblastoma after failure of conventional methods
Exclusion
- retinoblastoma judged curable by conventional methods
- patient judged unable to undergo the procedure
Key Trial Info
Start Date :
May 1 2006
Trial Type :
INTERVENTIONAL
Allocation :
ESTIMATED
End Date :
July 1 2009
Estimated Enrollment :
100 Patients enrolled
Trial Details
Trial ID
NCT00901238
Start Date
May 1 2006
End Date
July 1 2009
Last Update
December 17 2009
Active Locations (2)
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1
Memorial Sloan Kettering Cancer Center
New York, New York, United States, 10065
2
Weill Medical College of Cornell University
New York, New York, United States, 10065