Status:
COMPLETED
Olfaction in Patients With Parkinson's Disease Following Treatment With Rasagiline
Lead Sponsor:
Technische Universität Dresden
Conditions:
Parkinson´s Disease
Eligibility:
All Genders
18-64 years
Phase:
PHASE4
Brief Summary
There is convincing evidence from numerous studies using both psychophysical and electrophysiological approaches that olfaction is markedly reduced in Parkinson´s disease (PD). Data on the prevalence ...
Eligibility Criteria
Inclusion
- Parkinson´s disease, Hoehn \& Yahr stage ≤ III
- aged 18-64 yrs
- hyposmia/functional anosmia defined as TDI\<30
- written consent
Exclusion
- congenital olfactory loss
- significant infections of the nose and nasal sinuses
- diseases/states apart from PD which may significantly affect olfactory function, e.g., asthma, head trauma etc.
- dementia, psychiatric illness, addictive behaviour
- smoker
- severe liver disease
- pregnant or breastfeeding women
- any contraindication for the treatment with Rasagiline
- women without reliable contraception
Key Trial Info
Start Date :
May 1 2009
Trial Type :
INTERVENTIONAL
Allocation :
ACTUAL
End Date :
February 1 2012
Estimated Enrollment :
34 Patients enrolled
Trial Details
Trial ID
NCT00902941
Start Date
May 1 2009
End Date
February 1 2012
Last Update
February 7 2012
Active Locations (1)
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1
University of Dresden Medical School, Smell & Taste Centre, Dept. of Neurology
Dresden, Germany, 01307