Status:
WITHDRAWN
Treatment of Patients Colonized With Methicillin-Resistant Staphylococcus Aureus Prior to Bone and Joint Surgery
Lead Sponsor:
Bay Pines VA Healthcare System
Conditions:
Orthopedic Procedures
Methicillin-resistant Staphylococcus Aureus
Eligibility:
All Genders
Phase:
PHASE2
Brief Summary
The investigators anticipate that utilization of retapamulin preoperatively will eliminate MRSA colonization among patients who are colonized in their nares.
Detailed Description
Enhanced characterization of MRSA strains carried by patients and their eradication prior to surgery will significantly reduce healthcare costs to the VA by reducing the number of MRSA positive patien...
Eligibility Criteria
Inclusion
- Patients who are admitted for an orthopedic surgical procedure
- All patients will be screened and admitted to the study prior to surgery regardless of eventual culture results for MRSA
Exclusion
- Pregnancy
- Serious systemic illness due to renal, cardiac or hepatic disease
- Inability to complete follow-up assessments
- Allergy or intolerance to retapamulin
- BMI \> 30
- Uncontrolled diabetes, severe anemia, thrombocytopenia or an underlying hematopoietic disorder or malignancy
- Patients with serious life-threatening illnesses and those with terminal illness not expected to survive for two years or more will not be enrolled
- Antibiotics administered during the course of the study will be recorded (name, dose and dates)
Key Trial Info
Start Date :
August 1 2009
Trial Type :
INTERVENTIONAL
Allocation :
ACTUAL
End Date :
December 1 2010
Estimated Enrollment :
Patients enrolled
Trial Details
Trial ID
NCT00903279
Start Date
August 1 2009
End Date
December 1 2010
Last Update
January 31 2017
Active Locations (1)
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1
Bay Pines VAHCS
Bay Pines, Florida, United States, 33744