Status:

TERMINATED

Study To Investigate The Effectiveness Of Pregabalin For Management Of Patients Undergoing Total Hip Replacement

Lead Sponsor:

Pfizer's Upjohn has merged with Mylan to form Viatris Inc.

Conditions:

Pain, Perioperative

Eligibility:

All Genders

18+ years

Phase:

PHASE3

Brief Summary

The purpose of this study is the investigate if pregabalin started a day before surgery and continued for 14 days post-operatively can reduce post-operative pain, relieve pre- and post-operative anxie...

Eligibility Criteria

Inclusion

  • The patient is undergoing a routine (i.e., expected to be uncomplicated) total primary or secondary hip replacement surgery performed under a standardized regimen of spinal anesthesia, and is expected to experience moderate to severe post-surgical pain in the absence of post-operative analgesia

Exclusion

  • The patient is undergoing a revision to a previous hip replacement procedure, hip replacement procedure further to a road traffic accident with multiple injuries, or a procedure expected to last longer than 4 hours
  • The patient has a history of uncontrolled chronic disease or a concurrent clinically significant illness or medical condition, which in the Investigator's opinion, would contraindicate study participation or confound interpretation of the results

Key Trial Info

Start Date :

November 1 2009

Trial Type :

INTERVENTIONAL

Allocation :

ACTUAL

End Date :

July 1 2012

Estimated Enrollment :

72 Patients enrolled

Trial Details

Trial ID

NCT00905437

Start Date

November 1 2009

End Date

July 1 2012

Last Update

January 28 2021

Active Locations (7)

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Page 1 of 2 (7 locations)

1

Pfizer Investigational Site

Hyderabad, Andhra Pradesh, India, 500 033

2

Pfizer Investigational Site

Ahmedabad, Gujarat, India, 380 015

3

Pfizer Investigational Site

Bangalore, Karnataka, India, 560 076

4

Pfizer Investigational Site

Kanpur, Uttar Pradesh, India, 208 001