Status:

COMPLETED

Influence of Simvastatin on Apolipoprotein B-100 (apoB-100) Secretion

Lead Sponsor:

University Hospital, Bonn

Conditions:

Hypercholesterolemia

Eligibility:

MALE

18+ years

Phase:

NA

Brief Summary

3-Hydroxy-3-methylglutaryl coenzyme A-reductase inhibitors (statins) decrease apolipoprotein B-100-containing lipoproteins by increasing their fractional catabolic rates through low-density lipoprotei...

Detailed Description

3-Hydroxy-3 methylglutaryl (HMG) coenzyme A-reductase inhibitors (statins) have an established role in the treatment of hypercholesterolemia. Their efficacy in reducing cardiovascular morbidity and mo...

Eligibility Criteria

Inclusion

  • Hypercholesterolemia

Exclusion

  • Obesity
  • Treatment with lipid-lowering drugs

Key Trial Info

Start Date :

November 1 1998

Trial Type :

INTERVENTIONAL

Allocation :

ACTUAL

End Date :

March 1 2000

Estimated Enrollment :

8 Patients enrolled

Trial Details

Trial ID

NCT00905541

Start Date

November 1 1998

End Date

March 1 2000

Last Update

May 20 2009

Active Locations (1)

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Page 1 of 1 (1 locations)

1

University of Bonn

Bonn, Germany